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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VARS
All Species:
29.39
Human Site:
T496
Identified Species:
40.42
UniProt:
P26640
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26640
NP_006286.1
1264
140476
T496
E
V
D
K
K
E
L
T
G
R
T
L
L
S
V
Chimpanzee
Pan troglodytes
XP_001160008
1264
140384
T496
E
V
D
K
K
E
L
T
G
R
T
L
L
S
V
Rhesus Macaque
Macaca mulatta
Q5TM74
1064
118624
P400
K
V
T
P
A
H
S
P
A
D
A
E
M
G
A
Dog
Lupus familis
XP_538837
1256
139671
T496
E
V
D
K
K
E
L
T
G
R
T
L
L
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Q9
1263
140197
T495
E
V
D
K
K
E
L
T
G
R
T
L
L
P
V
Rat
Rattus norvegicus
Q04462
1264
140350
T496
E
V
D
K
K
E
L
T
G
R
T
L
L
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520676
985
109386
N322
R
S
S
V
A
E
P
N
P
R
G
V
F
M
M
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088439
1243
140617
S477
E
V
D
K
K
E
L
S
G
R
T
L
L
P
V
Zebra Danio
Brachydanio rerio
XP_682807
1111
123867
A432
D
M
N
F
G
T
G
A
V
K
I
T
P
A
H
Tiger Blowfish
Takifugu rubipres
P49696
1217
138200
S445
E
V
D
K
N
E
L
S
G
R
T
L
L
P
V
Fruit Fly
Dros. melanogaster
NP_524838
1049
118236
P386
T
G
A
V
K
I
T
P
A
H
D
P
N
D
Y
Honey Bee
Apis mellifera
XP_395202
1043
121057
I380
F
G
T
G
A
V
K
I
T
P
A
H
D
P
N
Nematode Worm
Caenorhab. elegans
Q9U1Q4
1050
118902
I387
H
N
D
Y
E
V
G
I
R
Q
N
L
P
F
H
Sea Urchin
Strong. purpuratus
XP_001200958
1119
126755
Y445
D
E
A
V
D
M
A
Y
G
T
G
A
V
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93736
1108
125908
N431
I
T
P
A
H
D
P
N
D
C
E
V
G
K
R
Baker's Yeast
Sacchar. cerevisiae
P07806
1104
125751
T432
A
V
D
M
E
F
G
T
G
A
V
K
I
T
P
Red Bread Mold
Neurospora crassa
P28350
1093
123334
A428
G
A
V
K
L
T
P
A
H
D
F
N
D
Y
Q
Conservation
Percent
Protein Identity:
100
99.5
43.4
92.8
N.A.
93.4
93.4
N.A.
63
N.A.
65.3
45
63.8
50.9
49.1
44.9
44.4
Protein Similarity:
100
99.8
56
95.6
N.A.
96.4
96.3
N.A.
69.8
N.A.
78
58.8
76.8
63.1
63.4
59.5
59.6
P-Site Identity:
100
100
6.6
100
N.A.
93.3
100
N.A.
13.3
N.A.
86.6
0
80
6.6
0
13.3
6.6
P-Site Similarity:
100
100
20
100
N.A.
93.3
100
N.A.
26.6
N.A.
93.3
33.3
86.6
6.6
0
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.6
42.6
40.3
Protein Similarity:
N.A.
N.A.
N.A.
58.3
60.1
56
P-Site Identity:
N.A.
N.A.
N.A.
0
26.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
46.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
12
6
18
0
6
12
12
6
12
6
0
6
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% C
% Asp:
12
0
53
0
6
6
0
0
6
12
6
0
12
6
0
% D
% Glu:
42
6
0
0
12
48
0
0
0
0
6
6
0
0
0
% E
% Phe:
6
0
0
6
0
6
0
0
0
0
6
0
6
6
0
% F
% Gly:
6
12
0
6
6
0
18
0
53
0
12
0
6
6
0
% G
% His:
6
0
0
0
6
6
0
0
6
6
0
6
0
0
12
% H
% Ile:
6
0
0
0
0
6
0
12
0
0
6
0
6
0
6
% I
% Lys:
6
0
0
48
42
0
6
0
0
6
0
6
0
12
0
% K
% Leu:
0
0
0
0
6
0
42
0
0
0
0
48
42
0
0
% L
% Met:
0
6
0
6
0
6
0
0
0
0
0
0
6
6
6
% M
% Asn:
0
6
6
0
6
0
0
12
0
0
6
6
6
0
6
% N
% Pro:
0
0
6
6
0
0
18
12
6
6
0
6
12
24
6
% P
% Gln:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
6
% Q
% Arg:
6
0
0
0
0
0
0
0
6
48
0
0
0
0
6
% R
% Ser:
0
6
6
0
0
0
6
12
0
0
0
0
0
24
0
% S
% Thr:
6
6
12
0
0
12
6
36
6
6
42
6
0
6
0
% T
% Val:
0
53
6
18
0
12
0
0
6
0
6
12
6
0
42
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
0
0
6
0
0
0
0
0
6
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _